PDRN skin rejuvenation and quality at your fingertips
- Clínica Fabio Carramaschi

- Sep 16
- 2 min read
Learn all about the rejuvenation treatment that many have been looking for, based on salmon DNA

We've already talked a few times on social media about PDRN ( Polydeoxyribonucleotide) treatment, better known as salmon DNA. But now we've put together a dossier with key information that will answer your questions about this treatment that has been attracting celebrities worldwide, such as Jennifer Aniston, Tom Cruise, and, in Brazil, actress Juliana Paes and TV presenter Tatá Werneck. Check out some insights from Dr. Flávia Piza, an expert in this protocol, below!
1. Why is salmon DNA gaining so many followers in skin rejuvenation?
PDRN, or salmon DNA, which is a compound derived from the DNA of this fish, has regenerative properties, which help in rejuvenation.
2. Where did this idea come from?
Its use has been studied since the 1960s. The inspiration comes from the ancient practice of Japanese fishermen who used salmon meat to heal their wounds.
3. Why is this treatment effective?
In addition to helping with cell regeneration by promoting collagen synthesis, its anti-inflammatory and angiogenic properties act on the formation of blood vessels, improving skin circulation.
4. What are the main benefits for the skin?
Improves hydration and combats collagen degradation caused by the sun, smoking, and oxidative stress. Resulting in an anti-aging effect by targeting fine lines and improving skin density, elasticity, and uniformity.
5. Can it be used in conjunction with other skin treatments?
Yes, we usually recommend it in conjunction with a biostimulator or whatever is most appropriate for the specific case. Patients who already have a Botox routine can continue without any problems. I always recommend that patients come with some questions and suggest treatments, like this one, but it's only during the consultation that we define the ideal protocol for best results, because each person is unique.



